Can Mounjaro and Wegovy cause Hair Loss?
Why Does Hair Loss Occur During Weight Loss?
Hair loss during weight loss is often attributed to telogen effluvium (TE), a temporary condition where a higher percentage of hair follicles enter the resting (telogen) phase, leading to excessive shedding. This can occur due to:
Rapid weight loss – Sudden caloric restriction can cause stress on the body, triggering hair shedding.
Nutrient deficiencies – Lack of essential vitamins and minerals can weaken hair structure.
Hormonal changes – Fluctuations in insulin and thyroid hormones can contribute to hair loss.
Increased stress levels – Psychological and physical stress from weight loss can impact hair cycles.
How GLP-1 Medications May Contribute to Hair Loss
GLP-1 receptor agonists like Mounjaro, Wegovy, and Ozempic are widely used for weight management and diabetes, but some users report increased hair shedding. The potential mechanisms include:
Nutrient Deficiencies Due to Appetite Suppression
GLP-1 medications significantly reduce appetite, leading to lower caloric intake and potential nutrient deficiencies that affect hair growth.
Deficiencies in iron, zinc, biotin, vitamin D, and protein are particularly linked to hair thinning.
Telogen Effluvium from Rapid Weight Loss
Studies suggest that losing more than 5-10% of body weight in a short period can trigger telogen effluvium, causing temporary hair shedding.
GLP-1 medications can accelerate weight loss, increasing the likelihood of this phenomenon.
Altered Insulin and Thyroid Function
GLP-1 medications impact insulin regulation, and some research suggests a connection between insulin resistance and hair thinning.
Thyroid function can also be affected, as weight loss influences T3 and T4 levels, which are essential for hair growth.
Inflammatory and Gut Microbiome Changes
The gut-brain axis plays a key role in immune regulation, and GLP-1 drugs can alter the gut microbiome, influencing scalp inflammation and follicular health.
How to Minimise Hair Loss While on GLP-1 Therapy
If you’re experiencing hair thinning while on a GLP-1 medication, consider the following strategies:
1. Ensure Adequate Nutrient Intake
Protein: Aim for at least 1.2-1.5g of protein per kg of body weight to support hair growth.
Iron: Found in red meat, spinach, and lentils, iron is essential for hair follicle function.
Zinc & Biotin: These micronutrients play a key role in keratin production and hair health.
Vitamin D: Supports hair follicle cycling and immune regulation.
2. Consider Hair Supplements
Collagen Peptides – May help with hair strength and scalp health.
Multivitamins with B-complex – Support metabolic functions that impact hair growth.
Omega-3 Fatty Acids – Reduce inflammation and support scalp circulation.
3. Avoid Excessive Caloric Restriction
While GLP-1 medications reduce appetite, it’s crucial not to under-eat. Ensure you consume enough calories to support cell turnover and hair follicle activity.
4. Support Scalp Health
Use topical minoxidil (Regaine) to stimulate hair regrowth.
Gentle scalp massage with oils like rosemary or peppermint may promote circulation.
Avoid excessive heat styling and harsh chemical treatments.
When to Speak to a GP or Dermatologist
If your hair loss is:
- Severe or prolonged (lasting more than 6 months)
- Accompanied by scalp irritation or bald patches
- Linked to additional symptoms like fatigue, brittle nails, or menstrual changes (could indicate underlying hormonal or thyroid imbalances)
A healthcare provider can conduct blood tests for ferritin, vitamin D, thyroid function, and insulin resistance to rule out underlying deficiencies or metabolic issues.
Hair loss during weight loss and while using GLP-1 medications is often temporary and reversible. By ensuring proper nutrition, supplementation, and scalp care, you can minimise shedding and promote regrowth. If hair loss persists, seeking medical advice can help uncover any underlying deficiencies or conditions needing attention.
